To provide clients around the world with high quality telomere length diagnostic measurement services. Through our telomere testing we provide important diagnostic information that supports decision making for physicians to monitor and improve the health of their patients.
Our Telomere Testing Technology
Flow-FISH analysis has the unique advantage over other telomere length protocols by providing information on a variety of cell types from one blood sample. Fluorescent signals from telomeres are assessed on a single cell basis by flow cytometry, with patient results reported for lymphocytes, granulocytes, B-cells, naïve and memory T-cells, and NK cells.
All patient telomere length profiles are reported in relationship to age-matched controls and are available for all age ranges from pediatric to geriatric. This telomere reference curve was established by the study of over 800 healthy individuals between birth and 100 years of age. This more informative technique allows analysis and comparisons of the telomere length between different cell types and within one cell type, e.g. in differentiating between constitutional deficiencies and cell type specific deficiencies. Such studies have shown that the telomere length declines with age, and follows distinct patterns in T cells, B cells and hematopoietic precursor cells. Longitudinal studies of hematopoietic stem cell transplantation have shown a rapid telomere length decline in the first year after transplant followed by stabilization.
Our Research on Telomeres
The need for telomere length measurements in clinical and other research studies is rapidly increasing. In order to support scientists in their efforts to advance the field of telomere biology, RepeatDx is actively seeking partnerships. In addition to performing Flow FISH telomere testing, RepeatDx can help in areas of grant support and provide special discounts for multi-sample research contracts.
For more information on research collaborations please contact us.